Explain Cairns’s technique to measure the length of the DNA molecule.

John Cairns used the technique of autoradiography to produce photographs of DNA from the bacterium E. coli.

[Source: © Cold Spring Harbor Laboratory Press. Autoradiography of bacterium E. coli DNA - micrograph, The Chromosome of
Escherichia coli Cairns, J.P., 1963. Cold Spring Harbor Symposia, Quantitative Biology, 28(44).]

Which conclusion was drawn from his experiments?

A. The DNA in all organisms is circular.

B. DNA in E. coli naturally contains thymidine.

C. DNA replication is conservative.

D. The DNA in E. coli is 900 μm in length.

The image shows tetrads in the anther of a lily. A tetrad is a group of four cells, produced when one mother cell divides by meiosis. The tetrad indicated by the arrow contains a total of 48 chromosomes.

[Source: [Tetrad], 2012. [image online] Available at: https://www.iasprr.org/old/iasprr-pix/lily/tetrad.jpg [accessed: 4 April 2019]. Photo courtesy of Professor Scott D. Russell.]

What is the diploid number of the plant?

A. 12

B. 24

C. 48

D. 96

The image shows a karyogram.

The karyogram shown belongs to a human being.

[Source: Reproduced from Tennakoon J, Kandasamy Y, Alcock G, Koh TH. Edwards syndrome with double trisomy. Singapore Med J. 2008 Jul;49(7):e190-1. PMID: 18695855.]

What can be deduced from this karyogram?

A. The person is a male with Down syndrome.

B. The person is a female with Down syndrome.

C. The person is a male with a genetic disorder.

D. The person is a female with a missing chromosome.

The image shows chromosomes from an insect (2 n = 8).

Which pair of chromosomes are the sex chromosomes of this insect species?

A.  c and e

B.  a and h

C.  f and h

D.  a and e

A pregnant woman had fetal cells removed by chorionic villus sampling and tested. The following karyogram was produced.

[Source: Mediscan / Alamy Stock Photo]

What does this show?

A. The child is female with Down syndrome.

B. The child is female without Down syndrome.

C. The child is male with Down syndrome.

D. The child is male without Down syndrome.

Describe the structure of the DNA molecule.

Testing the chromosomes of a girl with Turner syndrome produced the following karyogram.

[Source: Turner’s syndrome karyotype 45,XO. This female lacks the second X chromosome present in the
normal karyotype. Symptoms include short stature, neck webbing, elbow deformity, widely spaced nipples with shield chest, primary amenorrhea, sexual infantilism and sterility. The ovaries are reduced to fibrous streaks. Also known as XO syndrome or ovarian short-stature syndrome. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0).]

The condition can result from non-disjunction occurring in anaphase I of meiosis in an egg cell. Two cells result from the first division, one of which would lead to Turner syndrome. Which chromosomes will be in the other cell (polar body) at the end of meiosis I?

A. 44 autosomes and X

B. 44 autosomes and XX

C. 22 autosomes and X

D. 22 autosomes and XX

The diploid number of chromosomes in humans (Homo sapiens) is 46 and the diploid number of chromosomes in rice (Oryza sativa) is 24.  What does this indicate about diploid chromosome numbers?

A. Plant species have a lower diploid number of chromosomes than animals.
B. Members of a species have the same diploid number of chromosomes.
C. The evolutionary progress of species is determined by the diploid number of chromosomes.
D. The complexity of the organisms is correlated to the diploid number of chromosomes.