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Date May 2019 Marks available 1 Reference code 19M.3.SL.TZ1.15
Level Standard level Paper Paper 3 Time zone Time zone 1
Command term Outline Question number 15 Adapted from N/A

Question

Vitamin D is converted from an inactive form to an active form by exposure to sunlight. The graph shows the mortality (death rate) from falls in women over 75 as a function of latitude (distance from the equator).

[Source: Food and Agriculture Organization of the United Nations, 1997, B E C Nordin,
Calcium in Health and Disease, www.fao.org/3/W7336T/w7336t04.htm#calcium%20in%20health%20
and%20disease. Reproduced with permission]

Vitamin D deficiency can cause low blood calcium concentrations (hypocalcemia). Very low blood calcium can have an impact on heart function. The first ECG is for a patient with normal blood calcium concentrations. The second ECG is for a patient who has very low blood calcium concentrations.

[Source: © International Baccalaureate Organization 2019]

Osteomalacia is a condition that can be caused by Vitamin D deficiency. Outline one effect of osteomalacia.

[1]
a.

Outline the relationship shown in the graph.

[1]
b.i.

Suggest reasons for this relationship.

[2]
b.ii.

Compare and contrast the two ECG traces.

[2]
c.i.

Outline one event that occurs in the heart during the T wave.

[1]
c.ii.

Markscheme

softened/weakened bones/bone pain/increased fractures/difficulty walking/stunted growth ✔

a.

a. direct relationship/positive correlation ✔ 

b. increased latitude, higher mortality from falls ✔

Or vice versa

b.i.

a. higher latitude, lower levels of sunlight ✔

b. less uptake of calcium
OR
less vitamin D ✔

c. higher incidence of osteomalacia leads to higher risk of broken bones/mortality ✔

b.ii.

compare:
a. no difference in the P wave/QRS wave
OR
both traces have all 4 waves/PQRST ✔

contrast:
b. delayed T wave
OR
T wave is shorter/higher in hypocalcemia ✔

Allow reference to events in the cardiac cycle for mpa or mpb

Allow converse statements for mpb.

c.i.

a. repolarization of ventricles ✔ 

b. ventricles are in diastole/relaxation ✔

c.ii.

Examiners report

Osteomalacia producing weak bones was a common answer. Low calcium levels were also mentioned but this is a cause not an effect of osteomalacia.

a.

Nearly all candidates recognized a positive correlation.

b.i.

Lack of sunlight leading to less Vitamin D was the most common answer here. Calcium was rarely mentioned.

b.ii.

A difference between the traces was more often seen than a similarity, although many candidates gained the two marks.

c.i.

Many candidates did not know that ventricular diastole occurs during the T wave.

c.ii.

Syllabus sections

Option D: Human physiology » Option D: Human physiology (Core topics) » D.1 Human nutrition
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Option D: Human physiology » Option D: Human physiology (Core topics)
Option D: Human physiology

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