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Date November 2017 Marks available 1 Reference code 17N.2.HL.TZ0.02
Level Higher level Paper Paper 2 Time zone TZ0 / no time zone
Command term State Question number 02 Adapted from N/A

Question

State the role of plasma cells in the immune system.

[1]
c.

Describe the production of hybridoma cells.

[2]
d.i.

State one possible use of hybridoma cells.

[1]
d.ii.

Markscheme

produce/secrete antibodies

c.

a. antigen injected into mouse/mammal/host

    Accept animal

b. B cells/B lymphocytes/plasma cells «obtained/extracted from host»

c. fusion «of plasma cell» with myeloma cell/tumour cell

d. division «of hybridoma cells» to produce a clone

[Max 2 Marks]

 

d.i.

produce monoclonal antibodies
OR
diagnosis of diseases/malaria/cancer/HIV
OR
treatment of rabies
OR
blood and tissue typing
OR
pregnancy testing
OR
targeting of cancer cells «with a chemotherapy drug»
OR
treatment of infection if too late for vaccination/successful immune response

Only accept the first use of hybridoma cells given in the answer

Not treatment of malaria

 

d.ii.

Examiners report

[N/A]
c.
[N/A]
d.i.
[N/A]
d.ii.

Syllabus sections

Additional higher level » Topic 11: Animal physiology
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